Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consortium

Christine Fischer; Karoline Kuchenbäcker; Christoph Engel; Silke Zachariae; Kerstin Rhiem; Alfons Meindl; Nils Rahner; Nicola Dikow; Hansjörg Plendl; Irmgard Debatin; Tiemo Grimm; Dorothea Gadzicki; Ricarda Flöttmann; Judit Horvath; Evelin Schröck; Friedrich Stock; Dieter Schäfer; Ira Schwaab; Christiana Kartsonaki; Nasim Mavaddat; Brigitte Schlegelberger; Antonis C Antoniou; Rita Schmutzler; on behalf of the German Consortium for Hereditary Breast and Ovarian Cancer

doi:10.1136/jmedgenet-2012-101415

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Cancer genetics

Original article

Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consortium

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	Abstract	Full	Pdf
Apr 2013	443	75	109
May 2013	996	69	111
Jun 2013	483	24	44
Jul 2013	256	45	48
Aug 2013	156	23	29
Sep 2013	137	40	37
Oct 2013	199	57	73
Nov 2013	171	40	40
Dec 2013	180	52	44
Jan 2014	118	51	49
Feb 2014	44	35	31
Mar 2014	47	54	34
Apr 2014	90	52	30
May 2014	42	31	24
Jun 2014	61	41	40
Jul 2014	51	41	23
Aug 2014	39	27	16
Sep 2014	29	34	26
Oct 2014	53	19	10
Nov 2014	55	20	15
Dec 2014	54	11	8
Jan 2015	61	9	11
Feb 2015	44	16	15
Mar 2015	75	15	17
Apr 2015	50	14	15
May 2015	45	14	18
Jun 2015	36	23	13
Jul 2015	41	10	8
Aug 2015	34	12	10
Sep 2015	54	7	9
Oct 2015	37	8	11
Nov 2015	42	9	10
Dec 2015	44	12	8
Jan 2016	82	8	6
Feb 2016	41	9	10
Mar 2016	40	6	7
Apr 2016	14	13	8
May 2016	38	12	12
Jun 2016	33	5	9
Jul 2016	25	11	11
Aug 2016	42	12	11
Sep 2016	34	14	12
Oct 2016	41	11	6
Nov 2016	41	8	10
Dec 2016	36	4	2
Jan 2017	66	13	9
Feb 2017	42	11	7
Mar 2017	42	13	9
Apr 2017	39	8	8
May 2017	31	11	13
Jun 2017	56	18	5
Jul 2017	98	11	9
Aug 2017	122	4	6
Sep 2017	134	6	2
Oct 2017	128	11	5
Nov 2017	128	5	2
Dec 2017	208	11	6
Jan 2018	165	15	6
Feb 2018	115	12	9
Mar 2018	162	18	9
Apr 2018	148	6	4
May 2018	149	11	10
Jun 2018	111	10	5
Jul 2018	144	12	12
Aug 2018	143	8	9
Sep 2018	119	6	14
Oct 2018	184	6	12
Nov 2018	319	4	11
Dec 2018	100	3	4
Jan 2019	147	3	15
Feb 2019	130	19	17
Mar 2019	137	3	5
Apr 2019	145	6	6
May 2019	151	8	8
Jun 2019	58	6	6
Jul 2019	84	7	2
Aug 2019	128	4	2
Sep 2019	71	7	2
Oct 2019	90	12	7
Nov 2019	60	10	6
Dec 2019	99	1	0
Jan 2020	117	4	4
Feb 2020	113	13	7
Mar 2020	99	4	1
Apr 2020	65	5	3
May 2020	101	5	10
Jun 2020	140	9	8
Jul 2020	102	3	5
Aug 2020	76	4	4
Sep 2020	118	4	2
Oct 2020	68	8	3
Nov 2020	81	3	2
Dec 2020	78	1	4
Jan 2021	48	3	8
Feb 2021	75	7	3
Mar 2021	50	3	3
Apr 2021	83	10	5
May 2021	79	4	4
Jun 2021	17	14	10
Jul 2021	5	2	5
Aug 2021	5	4	4
Sep 2021	11	10	6
Oct 2021	96	4	5
Nov 2021	84	8	2
Dec 2021	59	8	8
Jan 2022	110	5	3
Feb 2022	70	5	5
Mar 2022	74	6	5
Apr 2022	130	8	0
May 2022	203	5	2
Jun 2022	142	11	8
Jul 2022	125	8	3
Aug 2022	177	11	8
Sep 2022	128	21	7
Oct 2022	111	10	2
Nov 2022	211	10	4
Dec 2022	81	7	1
Jan 2023	81	5	3
Feb 2023	91	4	0
Mar 2023	48	4	4
Apr 2023	59	3	3
May 2023	57	2	2
Jun 2023	43	1	0
Jul 2023	38	0	0
Aug 2023	42	4	2
Sep 2023	48	4	2
Oct 2023	101	4	2
Nov 2023	90	20	1
Dec 2023	105	7	1
Jan 2024	149	4	1
Feb 2024	78	3	0
Mar 2024	81	10	0
Total	13430	1744	1537

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