Table 2
Association of the SNP rs716508 and hand OA in replication samples
| rs716508 | |||
| MAF | β (SE) | p Value | |
| Chingford study | 0.31 | −0.18 (0.06) | 0.004 |
| CSAS | 0.29 | −0.25 (0.10) | 0.009 |
| GARP study | 0.33 | −0.10 (0.08) | 0.20 |
| Rotterdam study (rss) | 0.34 | −0.08 (0.04) | 0.07 |
| Meta-analysis | – | −0.12 (0.03) | 1.81×10−5 |
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β, regression coefficient; Chr, chromosome; CSAS, Chuvasha Skeletal Aging Study; GARP, Genetics, Arthrosis, and Progression; MAF, minor allele frequency; rss, replication subset; SNP, single-nucleotide polymorphism.
