| Patient | Control | |
| EI* | 5.68 (0.66)** (n = 24) | 11.71 (2.36) (n = 12) |
| Secondary clefts per primary cleft length | 1.82 (0.19) (n = 24) | 1.79 (0.14) (n = 12) |
| Nerve terminal area (μm2) | 3.73 (0.53)*** (n = 24) | 7.34 (0.93) (n = 12) |
| Number of synaptic vesicles/μm2 | 9.48 (1.14)** (n = 23) | 16.77 (2.77) (n = 12) |
| Cleft width (μm) | 0.16 (0.030)** (n = 11) | 0.074 (0.0036) (n = 12) |
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*EI, endplate index (postsynaptic membrane length/presynaptic membrane length).
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Values reported as mean (SEM).
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**p<0.05; ***p<0.001.









