Table 5 Stratification of phenotypic data by PrPSc (molecular strain) type (according to the London classification27), according to SPRN genotypes in patients with sporadic Creutzfeldt–Jakob disease
| Genotype c.20 | Age at disease onset (years) | Duration of disease (months) | PrPSc type | |||||||
| 1 | 2 | 3 | 2 + 3 | |||||||
| Mean | SD | Median | Mean | SD | Median | |||||
| TT | 55.3 | 21.5 | 62 | 9.1 | 13.6 | 5 | 6 | 33 | 9 | 2 |
| CT | 52.8 | 23.3 | 61 | 6.6 | 7.5 | 4 | 5 | 17 | 11 | 0 |
| CC | 57.3 | 27.2 | 68 | 7.3 | 4.8 | 7 | 1 | 3 | 1 | 0 |
-
SD, standard deviation.
