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Carriers of mild CFTR mutations risk chronic pancreatitis

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A sequencing study has settled the question whether mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene predispose to idiopathic chronic pancreatitis (ICP). They do—not just when occurring in compound heterozygotes but in cystic fibrosis carrier states with rare/mild CFTR mutations so the risk of ICP in white populations …

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