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J Med Genet 42:e40 doi:10.1136/jmg.2005.031492
  • Correspondence

Transmission of mutant alleles to female offspring of BRCA1 carriers in Poland

Table 1

 Number of mutation positive and negative first degree female relatives of BRCA1 mutation carriers in Poland

Year of birth Number positive Number negative Transmission ratio p value
–1950 10 11 48% 0.8
1951–1960 40 29 58% 0.3
1961–1970 36 28 56% 0.3
1971–1980 71 40 64% 0.003
1981–present 42 49 46% 0.9
Total 199 157 56% 0.03

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