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J Med Genet 41:710-714 doi:10.1136/jmg.2004.019257
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Novel locus on chromosome 12q22–q23.3 responsible for familial temporal lobe epilepsy associated with febrile seizures

Table 1

 Two point logarithm of odds scores

Marker Position LOD score Z at recombination fraction (θ = )
cM Mb 0.00 0.01 0.05 0.10 0.20 0.30 0.40
Positions of markers were obtained from the Marshfield comprehensive genetic map and the UCSC genome browser. Markers from the ABI linkage mapping set are boxed. The marker with the highest LOD score is emboldened.
D12S326 86.40 76.48 −5.81 −3.90 −1.94 −1.00 −0.18 0.08 0.07
D12S351 95.56 90.41 −0.40 −0.15 0.37 0.61 0.69 0.55 0.30
D12S322 96.09 90.72 −4.50 −3.87 −2.33 −1.41 −0.57 −0.27 −0.14
D12S829 97.16 93.12 −1.40 1.03 2.08 2.38 2.18 1.54 0.71
D12S101 100.92 94.10 −1.50 0.83 1.74 2.05 1.98 1.48 0.74
D12S348 100.92 95.05 3.82 3.80 3.80 3.45 2.77 1.84 0.74
D12S1716 101.45 95.45 5.98 5.93 5.71 5.33 4.31 3.00 1.42
D12S1051 101.98 96.07 6.34 6.29 6.05 5.66 4.61 3.25 1.61
D12S1706 104.12 97.37 6.94 6.85 6.45 5.90 4.60 3.07 1.31
D12S1727 107.19 100.20 5.92 5.82 5.42 4.88 3.67 2.33 0.97
D12S1607 107.86 100.76 6.84 6.77 6.47 6.00 4.83 3.38 1.65
D12S1030 109.47 101.43 3.92 3.87 3.65 3.33 2.57 1.67 0.71
D12S318 109.47 101.43 6.78 6.70 6.34 5.83 4.62 3.15 1.45
D12S360 111.27 102.58 1.71 2.81 3.15 3.01 2.39 1.57 0.65
D12S78 111.87 102.77 2.93 4.11 4.56 4.49 3.78 2.67 1.30
D12S1344 119.55 110.74 −1.26 −0.34 0.91 1.52 1.80 1.47 0.75
D12S79 125.31 114.47 0.96 1.73 2.61 2.93 2.81 2.14 1.10
D12S86 134.54 117.58 −2.76 −1.47 0.31 1.20 1.73 1.48 0.77

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