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J Med Genet 41:e74 doi:10.1136/jmg.2003.013151
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Haplotype analysis of human AMPD1 gene: origin of common mutant allele

Table 4

Catalytic activity of recombinant APD1 expressed in E. coli

AMPD activity IU/g protein Apparent KmAMP (mmol/l)
rat AMPD1 wild 23.8±3.7 3.8±0.4
rat AMPD1 K287I 11.8±2.5 7.3±1.3
rat AMPD1 M310I 7.8±1.2 7.6±1.0

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