rss
J Med Genet 41:224-229 doi:10.1136/jmg.2003.013201
  • Letters to JMG

A new locus for recessive distal spinal muscular atrophy at Xq13.1–q21

Table 3

Two point lod scores between the polymorphic markers derived from the X chromosome of the Brazilian distal SMA family

Locus θ =  Zmax θmax
0 0.05 0.10 0.15 0.20 0.25 0.3 0.35 0.40
DXS991 −∞ −1.66 −0.74 −0.28 −0.02 0.12 0.18 0.20 0.17 0.27 0.279
DXS1216 0.18 0.15 0.12 0.10 0.07 0.05 0.03 0.02 0.01 0.18 0.000
DXS8111 −∞ 2.08 2.12 2.01 1.84 1.62 1.36 1.08 0.75 2.13 0.081
DXS1275 −∞ 2.10 2.13 2.02 1.84 1.62 1.37 1.08 0.76 2.14 0.080
DXS8031 −∞ 2.08 2.12 2.01 1.84 1.62 1.36 1.08 0.75 2.13 0.081
DXS8107 −∞ 2.06 2.09 1.99 1.82 1.61 1.36 1.07 0.75 2.11 0.083
DXS8052 2.45 2.26 2.06 1.85 1.63 1.40 1.15 0.89 0.61 2.45 0.000
DXS8046 −∞ 1.40 1.48 1.43 1.32 1.17 0.99 0.78 0.55 1.48 0.098
DXS8060 2.93 2.70 2.45 2.20 1.93 1.65 1.36 1.05 0.72 2.93 0.000
DXS8092 2.45 2.26 2.06 1.85 1.63 1.40 1.15 0.89 0.61 2.45 0.000
DXS986 5.73 5.28 4.80 4.30 3.78 3.23 2.65 2.04 1.40 5.73 0.000
DXS1002 5.67 5.21 4.74 4.25 3.73 3.18 2.61 2.01 1.37 5.67 0.000
DXS1196 4.80 4.42 4.02 3.60 3.15 2.69 2.20 1.69 1.15 4.81 0.000
DXS1217 0.93 0.85 0.77 0.69 0.60 0.51 0.42 0.32 0.22 0.93 0.000
DXS990 −∞ 4.25 4.08 3.77 3.38 2.94 2.44 1.90 1.31 4.25 0.048
DXS8077 −∞ 4.25 4.08 3.77 3.38 2.94 2.44 1.90 1.31 1.49 0.085
DXS8020 −∞ 1.44 1.49 1.40 1.24 1.05 0.83 0.59 0.35 4.25 0.048
DXS1106 −∞ 2.99 3.15 3.03 2.79 2.47 2.09 1.64 1.15 3.15 0.096

This Article

Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of JMG.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

  • Latest genetics jobs

    Latest genetics jobs