Table 2
Overview of peaks revealed with the GeneChip Mapping 10K SNP array
| Chromosomal location | P2 | P4* | P5 | P12 | P16 | P17 |
|---|---|---|---|---|---|---|
| Peaks were defined as a minimum of three contiguous SNPs with a CPA p value of at least ±8. *Hybridisation with generally low signal intensity showing only one site with four contiguous SNPs with a CPA p value of ⩽−5. Peak values correctly identified as significant peaks: †deletion, ‡duplication; §reproducible peak considered not disease related, because it was mainly produced by a very low copy number of a single SNP within a region without known genes; ¶false positive peaks, not confirmed by either repeat hybridisation, quantitative PCR or FISH. N, normal; het, peak not considered because two SNPs within the peak region were heterozygous (peak also not reproducible). Number of SNPs showing respective CPA p value are shown in parentheses. | ||||||
| 2 (77.4–79.5 M) | N | N | N | 20 (10x)¶ | N | N |
| 4 (0–2.1 M) | N | N | N | −10.3 (3x)† | N | N |
| 4 (79.8–80.4 M) | N | N | N | N | −20 (9x)† | N |
| 4 (118.8–119.3 M) | N | N | 20 (4x)¶ | N | N | N |
| 5 (145.7–146.0 M) | N | N | −10.4 (5x)§ | N | N | N |
| 5 (178.4-TER) | N | −5.2 (4x)† | N | N | N | N |
| 9 (35.5–38.3 M) | N | N | N | N | N | −8.8 (5x) het |
| 10 (131.1–132.6 M) | N | N | −20 (12x)† | N | N | N |
| 11 (17.9–18.1 M) | N | N | N | −8.7 (4x)¶ | N | N |
| 22 (16.6–19.7 M) | −8.6 (6x)† | N | N | N | N | N |
| 22 (43.9–46.4 M) | N | N | 20 (12x)‡ | N | N | N |
| X (PTER-7.5 M) | Male (−20) | N | N | N | Male (−20) | −11.7 (9x)† |
