rss
J Med Genet 40:e91 doi:10.1136/jmg.40.8.e91
  • Electronic letters

Individual and family characteristics associated with protein truncating BRCA1 and BRCA2 mutations in an Ontario population based series from the Cooperative Family Registry for Breast Cancer Studies

Table 5

BRCA1 and BRCA2 mutation carrier status and the presence of ovarian cancer in the family

Cases No BRCA1 No (%) BRCA2 No (%) BRCA1 or BRCA2 No (%)
*Relatives diagnosed with ovarian cancer at age ⩽60 in the first, second, or third degree relationship.
Presence of ovarian cancers (total 314):*
Yes 40 6 (15.0) 2 (5.0) 8 (20.0)
No 274 11 (4.0) 12 (4.4) 23 (8.4)
p value 0.01 1.00 0.03

This Article

Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of JMG.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

  • Latest genetics jobs

    Latest genetics jobs