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J Med Genet 40:515-519 doi:10.1136/jmg.40.7.515
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A gene locus for branchio-otic syndrome maps to chromosome 14q21.3-q24.3

Table 2

Two point lod scores generated in the BOS kindred at various recombination fractions for markers at the BOS3 locus

Two point lod scores at recombination fraction θ=
Marker 0 0.001 0.01 0.05 0.1 0.2 0.3 0.4 Zmax (θ)
D14S599 −4.991 −3.645 −1.891 −0.659 −0.237 0.02 0.053 0.028 0.053 (0.3)
D14S306 −4.220 −2.777 −0.984 0.192 0.529 0.585 0.381 0.127 0.585 (0.2)
D14S1013 −0.135 0.624 1.494 1.926 1.892 1.492 0.953 0.419 1.926 (0.05)
D14S748 1.902 1.898 1.853 1.656 1.410 0.934 0.508 0.182 1.902 (0.0)
D14S587 3.268 3.261 3.202 2.933 2.590 1.881 1.170 0.518 3.268 (0.0)
D14S980 4.114 4.107 4.038 3.726 3.321 2.461 1.544 0.638 4.114 (0.0)
D14S274 2.163 2.157 2.097 1.830 1.492 0.831 0.286 0.005 2.163 (0.0)
D14S592 2.672 2.666 2.612 2.371 2.067 1.459 0.876 0.368 2.672 (0.0)
D14S588 1.962 1.958 1.922 1.756 1.544 1.108 0.679 0.298 1.962 (0.0)
D14S1002 3.359 3.353 3.295 3.033 2.696 1.995 1.275 0.583 3.359 (0.0)
D14S1025 2.254 2.249 2.201 1.988 1.717 1.166 0.634 0.214 2.254 (0.0)
D14S53 0.324 1.064 1.925 2.335 2.272 1.816 1.208 0.568 2.335 (0.05)
D14S606 −4.205 −2.769 −0.981 0.188 0.517 0.568 0.388 0.173 0.568 (0.2)

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