Table 3
Distribution of CSK alleles in familial and sporadic spina bifida aperta patients (group I) and controls
| Alleles n (%) | ||||||
|---|---|---|---|---|---|---|
| 210C>T | 759C>T | 792C>T | ||||
| C | T (%) | C | T (%) | C | T (%) | |
| *Except for the 210C>T polymorphism for which 72 sporadic patients were included resulting in a total of 108 spina bifida aperta patients for this specific analysis. | ||||||
| †Unaffected and unrelated subjects were randomly chosen from the Dutch population and used as a control group. | ||||||
| Familial patients (36) | 71 | 1 (1.4) | 69 | 3 (4.2) | 71 | 1 (1.4) |
| Sporadic patients (73*) | 141 | 3 (2.1) | 141 | 5 (3.4) | 143 | 3 (2.1) |
| Total (109*) | 212 | 4 (1.9) | 210 | 8 (3.7) | 214 | 4 (1.8) |
| Controls (52†) | 102 | 2 (1.9) | 99 | 5 (4.8) | 102 | 2 (1.9) |
