Table 1
Results of the FISH analysis to characterise the extent of chromosome 3 derived DNA on the marker described here in comparison with the marker chromosomes described by Portnoï et al1 and Kroisel et al6
| Absence (−)/presence (+) of FISH signal on the der(3) chromosome of the patient described | ||||||
|---|---|---|---|---|---|---|
| Probes used for FISH analysis | Marker | GenBank Accession number | Assignment to band on chromosome 3 | This study | Portnoï et al1 | Kroisel et al6 |
| *The additional material is attached distally to the subtelomeric end at 3q thus forming an elongated 3q+ chromosome. | ||||||
| †KNG (Kininogen precursor gene). | ||||||
| ND: not determined. | ||||||
| +, ++, +++ single, double, triple FISH signal. | ||||||
| YAC 806d8 | D3S3520 | q26.31 | ND | – | +* | |
| YAC 760f3 | D3S3699 | q26.32 | – | ++ | +* | |
| YAC 781f8 | D3S513 | ND | ++ | +++* | ||
| YAC 906c11 | D3S1571 | q27.1 | – | ND | ND | |
| YAC 909d10 | KNG† | q28 | – | ND | ND | |
| D3S1314 | q28 | |||||
| YAC 883d12 | KNG† | q28 | ND | ++ | +++* | |
| BAC RP11-814o5 | D3S3076 | AC062008 | q28 | – | ND | ND |
| BAC RP11-634l24 | AC041034 | q28 | ++ | |||
| BAC RP11-69j10 | AC026518 | q29 | ++ | |||
| BAC RP11-221n10 | AC067896 | q29 | ++ | |||
| BAC RP11-496h1 | AC024560 | q29 | ++ | |||
| YAC 763e7 | D3S1272 | q29 | ++ | ND | ND | |
| YAC 919f12 | D3S1272 | q29 | ND | ND | ND | |
| pVYS223B | 3QTEL05 | q29 | ++ | ND | +++* | |
