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Transient transfection permits analysis of mismatch repair genes

https://doi.org/10.1136/jmg.40.2.86

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    How variants of mismatch repair genes affect development of colorectal cancer can now be studied much more easily, thanks to a method tested for this purpose by German researchers.

    They used a transient transfection model between wild type (wt) and two mutant DNA constructs of the major human mismatch repair (MMR) …

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