Dysmorphism, variable overgrowth, normal bone age, and severe developmental delay: a “Sotos-like” syndrome?

Table 2

Facial dysmorphic features in the five reported cases and four published cases compared to distinctive facial features in a series of patients with Sotos syndrome*

									Robertson and Bankier¹¹
Facial features	Sotos syndrome*	Case 1	Case 2	Case 3	Case 4	Case 5	Total	Suzuki et al¹⁰	Case 1	Case 2	Case 3	Total
*From Cole and Hughes.³
CL, cleft lip.

Frontal bossing	97.5%	+	+	+	+	+	5/5	+	+	+	+	4/4
High frontal hairline	97.5%	+	+	+	+	+	5/5	+	+	+	+	4/4
Prominent jaw	95%	+	+	+	+	+	5/5	−	?	+	+	2/3
Downward slanting palpebral fissures	90%	−	+	+	+	+	4/5	+	−	+	−	2/4
Facial flushing	85%	+	?	?	+	?	2/2	?	?	?	?	?
Dolichocephaly	80%	+	+	?	+	+	4/4	?	?	?	?	?
High palate	70%	+	CL	?	+	+	3/3	+	+	+	+	4/4

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Dysmorphism, variable overgrowth, normal bone age, and severe developmental delay: a “Sotos-like” syndrome?

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