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J Med Genet 38:617-621 doi:10.1136/jmg.38.9.617
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De novo terminal deletion of chromosome 15q26.1 characterised by comparative genomic hybridisation and FISH with locus specific probes

Table 1

Detection of chromosome 15q loci by FISH and microsatellite analysis

STS cM1-150 Probe (YAC clone) Method1-151 Normal chromosome 15 Derivative chromosome 15
D15S153 62.1 — MS + +
D15S114 72.3 — MS + +
D15S152 78.6 — MS NI NI
D15S199 81.9 913e02 FISH + +
D15S979 82.4 — MS + +
D15S1045 84.7 859c06 FISH + +
D15S127 84.8 — MS + +
D15S963 85.8 — MS + +
D15S652 88.0 — MS + +
D15S130 98.0 963d03 FISH + −
D15S130 98.0 — MS + −
D15S207/ 100.8 895h10 FISH + −
D15S157 103.5
D15S1014 103.5 — MS NI NI
D15S120/ 109.6 882h08 FISH + −
D15S203 109.6
D15S120 109.6 — MS NI NI
D15S966 110.2 — MS + −
D15S642 (119.8) — MS + −
D15S936 ? TelVysion 15q FISH + −
Telomere ? All telomeric probe FISH + +

  • ↵1-150 Genetic localisation according to Dib et al.12 The distance between D15S966 and D15S642 was obtained from Broman et al.13

  • ↵1-151 Loci were studied either by FISH with YAC clones or by analysis of microsatellites (MS).

  • +, allele detected; −, allele missing; NI, not informative.

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