A syndrome of immune complex glomerulonephritis and ophthalmic abnormalities
- aDepartment of Paediatrics, Faculty of Medicine and Health Sciences, UAE University, Post Box 17666, Al Ain, United Arab Emirates, bDivision of Nephropathology, Armed Forces Institute of Pathology, Washington DC, USA
- Dr Abdulrazzaq.
- Received 5 June 1998
- Revised 9 March 1999
Abstract
Two sibs (one male and one female) suffering from a combination of immune complex glomerulonephritis and various ophthalmologic disorders are presented. The two cases belong to a family in which the parents are not related and seven sibs are affected, three females and a male with the combination, and three males with severe ophthalmological changes and proteinuria. Clinically, case 2 had only ophthalmological manifestations but renal biopsy findings were similar to those of case 1, which could mean that all the others with eye abnormalities also had renal disease. Although there are several reports of combinations of eye and renal disorders, the sibs reported here do not fit into any of the known syndromes.
