Table of contents

Research Article

• An ancestral core haplotype defines the critical region harbouring the North Carolina macular dystrophy gene (MCDR1). (1 December, 1997)

  C G Sauer, H D Schworm, M Ulbig, A Blankenagel, K Rohrschneider, D Pauleikhoff, T Grimm, B H Weber
• Linkage studies in dominant optic atrophy, Kjer type: possible evidence for heterogeneity. (1 December, 1997)

  M J Seller, J T Behnam, C M Lewis, R L Johnston, M A Burdon, D J Spalton
• Genetic epidemiology of muscular dystrophies resulting from sarcoglycan gene mutations. (1 December, 1997)

  M Fanin, D J Duggan, M L Mostacciuolo, F Martinello, M P Freda, G Sorarù, C P Trevisan, E P Hoffman, C Angelini
• Muscular involvement in the Holt-Oram syndrome. (1 December, 1997)

  S Spranger, H Ulmer, J Tröger, O Jansen, J Graf, H M Meinck, M Spranger
• Analysis of spinocerebellar ataxia types 1, 2, 3, and 6, dentatorubral-pallidoluysian atrophy, and Friedreich's ataxia genes in spinocerebellar ataxia patients in the UK. (1 December, 1997)

  J Leggo, A Dalton, P J Morrison, A Dodge, M Connarty, M J Kotze, D C Rubinsztein
• Features of DiGeorge syndrome and CHARGE association in five patients. (1 December, 1997)

  P de Lonlay-Debeney, V Cormier-Daire, J Amiel, V Abadie, S Odent, A Paupe, S Couderc, A L Tellier, D Bonnet, M Prieur, M Vekemans, A Munnich, S Lyonnet
• BRCA1 and BRCA2 mutation analysis in 86 early onset breast/ovarian cancer patients. (1 December, 1997)

  A M Garvin, M Attenhofer-Haner, R J Scott
• Novel and characteristic CFTR mutations in Saudi Arab children with severe cystic fibrosis. (1 December, 1997)

  E A el-Harith, T Dörk, M Stuhrmann, H Abu-Srair, A al-Shahri, K M Keller, M J Lentze, J Schmidtke
• Effects of consanguineous marriage on reproductive outcome in an Arab community in Israel. (1 December, 1997)

  L Jaber, P Merlob, R Gabriel, M Shohat
• Genetic heterogeneity of Meckel syndrome. (1 December, 1997)

  J Roume, H W Ma, M Le Merrer, V Cormier-Daire, D Girlich, E Genin, A Munnich
• Peutz-Jeghers syndrome. (1 December, 1997)

  I P Tomlinson, R S Houlston
• Multiple congenital anomalies including the Rieger eye malformation in a boy with interstitial deletion of (4) (q25-->q27) secondary to a balanced insertion in his normal father: evidence for haplotype insufficiency causing the Rieger malformation. (1 December, 1997)

  A Schinzel, L Brecevic, F Dutly, A Baumer, F Binkert, R H Largo
• A new locus for non-syndromal, autosomal recessive, sensorineural hearing loss (DFNB16) maps to human chromosome 15q21-q22. (1 December, 1997)

  D A Campbell, D P McHale, K A Brown, L M Moynihan, M Houseman, G Karbani, G Parry, A H Janjua, V Newton, L al-Gazali, A F Markham, N J Lench, R F Mueller
• Dominantly inherited cerebral dysplasia: arachnoid cyst associated with mild mental handicap in a mother and her son. (1 December, 1997)

  J L Tolmie, R Day, B Fredericks, P Galea, A W Moffett
• Dentato-olivary dysplasia in sibs: an autosomal recessive disorder? (1 December, 1997)

  T Martland, B N Harding, R E Morton, I Young
• Genetic linkage analysis of 14 candidate gene loci in a family with autosomal dominant osteoarthritis without dysplasia. (1 December, 1997)

  I Meulenbelt, C Bijkerk, F C Breedveld, P E Slagboom
• Frequency of the G6PD nt 1311 C/T polymorphism in English and Iranian populations: relevance to studies of X chromosome inactivation. (1 December, 1997)

  Y Mortazavi, R Chopra, E C Gordon-Smith, T R Rutherford
• Evidence for a cryptic 46,XX cell line in a 45,X/46,X,psu idic(Xq) patient with normal reproduction. (1 December, 1997)

  R S James, A J Sharp, A E Cockwell, B Coppin, P A Jacobs
• Complete situs inversus and broad thumbs and big toes with postaxial polydactyly. (1 December, 1997)

  A E Czeizel, P Göblyös
• Molecular basis of mild hyperphenylalaninaemia in Poland. (1 December, 1997)

  C Zekanowski, M Nowacka, B Cabalska, J Bal
• Grebe syndrome: a second case with extremely severe manifestations. (1 December, 1997)

  M Rittler, S Higa