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The human genes for complement components 6 (C6) and 9 (C9) are closely linked on chromosome 5.
  1. S Rogne,
  2. O Myklebost,
  3. J H Olving,
  4. H T Kyrkjebø,
  5. R Jonassen,
  6. B Olaisen,
  7. T Gedde-Dahl, Jr
  1. Department of Animal Science, Agricultural University, Norway.

    Abstract

    We have used a cDNA probe for human complement component 9 (C9), which detects three DNA polymorphisms, to analyse the inheritance of C9 in families informative for C6 protein variants. We found that these genes are closely linked with a lod score of 9.28 at recombination fraction 0.00. There is not indication of allelic association.

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