Article Text

PDF

A Chinese familial growth hormone deficiency with a deletion of 7.1 kb of DNA.
  1. Y A He,
  2. S S Chen,
  3. Y X Wang,
  4. X Y Lin,
  5. D F Wang
  1. Department of Biochemistry, Shanghai Second Medical University, China.

    Abstract

    Using restriction endonuclease analysis and a human growth hormone cDNA probe, we have found a Chinese family with a human growth hormone gene deletion. Two affected sibs are homozygous for a deletion of approximately 7.1 kb of DNA, which contains the normal human growth hormone gene. The patients' parents and grandmothers are heterozygous for the deleted gene. Their grandfathers are normal and homozygous for the hGH-N gene. All of them have normal stature.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.