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A genetic linkage study of facioscapulohumeral (Landouzy-Déjérine) disease with 24 polymorphic DNA probes.
  1. M Upadhyaya,
  2. M Sarfarazi,
  3. P W Lunt,
  4. W Broadhead,
  5. P S Harper
  1. Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff.

    Abstract

    From analysis of DNA polymorphisms in a panel of 455 subjects from 25 families with facioscapulohumeral (Landouzy-Déjérine) disease, we have found no evidence for close linkage of the disease at 24 different genetic loci, including one from a candidate chromosomal region. Added to previous data, our results provide direction for future collaborative linkage studies.

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