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Linkage analysis of French families with facioscapulohumeral muscular dystrophy.
  1. G Lucotte,
  2. S Berriche,
  3. M Fardeau
  1. Laboratory of Physical Anthropology, Collège de France, Paris.

    Abstract

    Linkage analysis was undertaken in seven French families with facioscapulohumeral muscular dystrophy (FSHD). Six polymorphic DNA probes were studied, including random DNA sequences, coding sequences, and a hypervariable marker. No evidence for linkage of these probes to the disease was detected, and the results exclude probable location of the FSHD gene from three chromosomal regions (16p, proximal 19q, and 21q).

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