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J Med Genet 26:294-298 doi:10.1136/jmg.26.5.294
  • Research Article

Fertility in a male with trisomy 21.

  1. R Sheridan,
  2. J Llerena, Jr,
  3. S Matkins,
  4. P Debenham,
  5. A Cawood,
  6. M Bobrow
  1. Division of Medical and Molecular Genetics, United Medical School, Guy's Hospital, London.

      Abstract

      We review the published reports on reproduction in cases of non-mosaic trisomy 21 (Down's syndrome) and present the first fully documented case of a non-mosaic male with Down's syndrome fathering a pregnancy, a fact which has important implications in the light of caring for these people in the community.