Article Text

PDF

Prediction of consanguinity using human DNA fingerprints.
  1. R A Wells,
  2. B Wonke,
  3. S L Thein
  1. MRC Molecular Haematology Unit, John Radcliffe Hospital, Oxford.

    Abstract

    DNA fingerprinting was performed to verify the pedigree structure of a family under investigation for an unusual case of beta thalassaemia. A higher than expected proportion of hypervariable bands was shared by the proband and his mother, leading to suspicion that the child had been the product of a consanguineous mating. Further analysis of the mother's brother showed that he was almost certainly the proband's father.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.