Article Text

PDF

Linkage analysis of British and Indian families with Von Recklinghausen neurofibromatosis.
  1. C G Mathew,
  2. K Thorpe,
  3. D F Easton,
  4. C Carter,
  5. C Wallis,
  6. Z Wong,
  7. A J Jeffreys,
  8. B A Ponder
  1. Institute of Cancer Research, Haddow Laboratories, Sutton, Surrey.

    Abstract

    Linkage analysis has been undertaken in two British and three South African Indian families with Von Recklinghausen neurofibromatosis. Eleven polymorphic DNA probes were studied, including both random DNA sequences and candidate oncogenes. Although no evidence for linkage of these probes to the disease was detected, substantial exclusion regions were established on six of the chromosomes studied.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.