J Med Genet 19:473-476 doi:10.1136/jmg.19.6.473
  • Research Article

Cat-like cry and mental retardation owing to 7q interstitial deletion (7q22 leads to 7q32).


A patient with mental retardation and mild facial dysmorphism had a karyotype which was considered to be normal before the availability of chromosomal banding techniques. She had a history of a cat-like cry and severe feeding problems during infancy. At the age of 9, she was still found to have initial aphonia on trying to initiate sounds. Repeat chromosome analysis with G banding showed an interstitial deletion of the long arm of chromosome 7.