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Congenital hydrocephalus in two pregnancies following the birth of a child with a neural tube defect: aetiology and management.
  1. R D Robertson,
  2. D A Sarti,
  3. W J Brown,
  4. B F Crandall

    Abstract

    A family is described with congenital hydrocephalus occurring in two pregnancies following the birth of a child with a neural tube defect (NTD). Prenatal diagnosis of hydrocephalus at mid-gestation was achieved by ultrasonography. The increased frequency of hydrocephalus among sibs of probands with a NTD and vice versa suggests that, following the birth of a child with either malformations, subsequent pregnancies should be monitored at mid-gestation by amniotic fluid AFP and serial ultrasound examination.

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