You are here

Article Text

Article menu
Download PDFPDF
Research Article
Excess of cancer deaths in grandparents of patients with retinoblastoma.
  1. C Bonaïti-Pellié,
  2. M L Briard-Guillemot

    Abstract

    An excess of cancer deaths was found in grandparents of 308 children with retinoblastoma. This excess was found in all types of retinoblastoma, unilateral and bilateral, sporadic and familial. We postulated that the excess could be the result of a factor of susceptibility to cancer, different from the retinoblastoma gene, which would increase the mutation rate in retinal and germ cells as well as in other tissues.

    https://doi.org/10.1136/jmg.17.2.95

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.