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Reciprocal translocation, 4q-; 21p+, giving rise to Down's syndrome.
  1. M B Jenkins,
  2. L Boyd

    Abstract

    A reciprocal translocation is described, t(4;21)(q27;p11), which occurs in a balanced carrier mother and her Down's syndrome child, 47,XX,t(4q-;21p+),+21. A review is presented of Down's syndrome associated with reciprocal translations involving chromosome No. 21.

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