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New allele at cholinesterase locus 1.
  1. P J Garry,
  2. A A Dietz,
  3. T Lubrano,
  4. P C Ford,
  5. K James,
  6. H M Rubinstein

    Abstract

    A family (H-J pedigree) segregating for the A and F alleles at cholinesterase locus 1 is described. Apparent anomalous results led to the recognition of a new allele (E1j) also segregating in the family. The data are consistent with the hypothesis that the the E1j causes reduction of 'usual' (E1u) molecules by about 66%. Whether this is because of retarded synthesis or accelerated degradation of serum cholinesterase remains to be determined.

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