Article Text

PDF

Three Further Cases of Triploidy in Man Surviving to Birth
  1. S. Walker*,
  2. J. Andrews,
  3. N. M. Gregson,
  4. W. Gault††

    Abstract

    Three triploid infants, two male (69,XXY) and one female (69,XXX) all of which survived beyond 35 weeks' gestation are described. One was stillborn due to a difficult delivery, the other two survived for a few hours only. Two were of relatively low birth weight, the other was normal. There was no evidence of mosaicism in the tissue examined.

    In keeping with previously reported triploid infants they showed a variety of abnormalities. From a total of 13 cases now reported the more frequent associated anomalies are low set ears, coloboma of the iris, syndactyly of the hands, a single palmar crease, abnormal male genitalia in XXY individuals, polycystic kidney, and congenital heart defect. The most common anomaly, however, is hydatidiform degeneration of a large placenta.

    Statistics from Altmetric.com

    Footnotes

    • * Cytogenetics Unit, Nuffield Building, University of Liverpool.

    • Department of Obstetrics and Gynaecology, University of Liverpool. Present address: University Hospitals of Wales, Cardiff.

    • Cytogenetics Unit, Nuffield Building, University of Liverpool. Present address: Department of Pathology, General Infirmary, Salisbury.

    • †† Clatterbridge Hospital, Bebington, Cheshire.

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.