Letters to the editor
Familial non-medullary thyroid cancer in Iceland
| The first 150 words of the full text of this article appear below. |
EDITOR
Incidence of thyroid carcinoma in Iceland
is high1 and papillary carcinoma comprises 80% of all
thyroid malignancies in the country.2 It is well known
that medullary thyroid carcinoma aggregates in families and the genetic
component in the aetiology has been established.3 Familial
occurrence of non-medullary thyroid carcinoma is rare, but it has been
increasingly recognised in recent years.4-6 There has
been increasing awareness that this may constitute a distinct disease
subgroup rather than chance occurrence, as reflected by the review of
case series by Loh.7 Familial papillary microcarcinoma has
also been suggested as a new clinical entity.8 9 In an
earlier paper, we reported on the occurrence of papillary thyroid
carcinoma (373 probands) in first degree relatives of all patients
diagnosed between 1955 and 1984 in Iceland.10 This study
showed a non-significant trend to familiality. In the present study,
the population includes second and third degree relatives in addition
to first
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This article has been cited by other articles:
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Hemminki, K., Eng, C., Chen, B.
(2005). Familial Risks for Nonmedullary Thyroid Cancer. J. Clin. Endocrinol. Metab.
90: 5747-5753
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